GAPDH anticorps

N° du produit ABIN1107316

Cet anticorps Souris Monoclonal détecte spécifiquement GAPDH dans WB, EIA et DB. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Saccharomyces cerevisiae, Insectes et Bactéries.

Aperçu rapide pour GAPDH anticorps (ABIN1107316)

Antigène: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Reactivité: Humain, Souris, Rat, Lapin, Saccharomyces cerevisiae, Insectes, Bactéries

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GAPDH est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Dot Blot (DB)

Clone: H8

Détail du produit anti-GAPDH anticorps

Specificité: Recognizes native and recombinant GAPDH in Human, Mouse, Rat, Rabbit, sf9 Insect cells, Yeast and BL-21 Bacteria.

Purification: Purified

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in double distilled or deioned H2O to a concentration of 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur GAPDH

Antigène: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Autre désignation: GAPDH

Sujet: Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36 kDa subunits.Synonyms: CDABP0047, GAPD, Glyceraldehyde-3-Phosphate Dehydrogenase

ID gène: 2597